AND Cost effectiveness. For permission for commercial use of this work, please see paragraphs 4. It is well known that SSRIs can cause various types of sexual dysfunction. Preskorn SH.
J Affect Disord. Antidepressant drugs are compounds which are widely used in a variety of psychiatric disorders in the World especially in the treatment of depression, if required, with adjuvant methods such as neuromodulation, physical activity, or psychotherapy, and adjuvant supplements like omegapolyunsaturated fatty acids 71 — 73 although some studies questioned the requirement of antidepressant drugs in a variety of situations.
Tolerability, safety and pharmacoeconomics. Another study did not report any beneficial effects of Gingko Biloba to extract on none of the sexual activity phases in a double-blind placebo-controlled study while the placebo showed satisfaction in orgasmic function.
First of all, SSRI use should be short term as soon as possible. Exercise improves sexual function in women taking antidepressants: results from a randomized crossover trial. In fact, it should be accepted that the CBT approach to sexual dysfunction does not seem to be effective when it is used alone.
Preskorn SH. Because described gene expression changes are complex, and can involve persistent modifications of chromatin structure, it has been suggested that SSRI use can result in persistently altered cerebral gene expression leading to compromised catecholaminergic neurotransmission and neuroendocrine disturbances,  such as decreased testosterone levels  and reduced sperm counts .
For example, Montejo et al reported that ten percent of patients who took antidepressant agents including SSRIs experienced reversible sexual side effects.