Nondisjunction of sex chromosomes could cause in Stretford

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It is the leading cause of pregnancy wastage and is the most common known cause of mental retardation. Only in rare cases of a mosaicismthe presence of a normal cell line, in addition to the trisomic cell line, may support the development of a viable trisomy of the other chromosomes.

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  • Calvin Bridges and Thomas Hunt Morgan discovered the process of nondisjunction in dividing cells in the year This is one of the most common forms of chromosomal aberration that occurs in humans.
  • Nondisjunction : meiosis is the fundamental process that is behind sexual reproduction with the formation of offspring that are genetically unique from each other and ever from their parents. While meiosis certainly evolved from mitosis itself, the former had acquired few novel steps that are distinct from the latter: pairing of the homologous chromosomes , recombination between non-sister chromatids, inhibition of the separation of sister chromatids during meiosis I, and the absence of replication of chromosomes during meiosis II.
  • Human Chromosomal Disorders April 30, Karyotype preparation and analysis.

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Nondisjunction of sex chromosomes could cause in Stretford

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  • May 16,  · Sex chromosome aneuploidy is the term for an abnormal number of sex chromosomes. Normally, females have two X chromosomes, while males have one X and one Y. Nondisjunction can cause individuals to be born female with one X (Turner syndrome), female with three X chromosomes (Trisomy X), male with XXY (Klinefelter syndrome), or male with XYY (XYY syndrome). Feb 07,  · All monosomies of autosomal (non-sex) chromosomes are lethal. Sex chromosome trisomies are XXY or Klinefelter's syndrome, XXX or trisomy X, and XYY syndrome. Autosomal trisomies include trisomy 21 or Down syndrome, trisomy 18 or Edwards syndrome, and trisomy 13 or Patau syndrome. Trisomies of chromosomes aside from sex chromosomes or chromosomes 13,
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  • Jan 21,  · In the sex chromosomes of a cell, nondisjunction can cause some lesser-known diseases, such as Klinefelter syndrome (a male with 2X and 1 Y), Turner syndrome (a female with only one X chromosome), or Trisomy X (female with 3 X chromosomes instead of 2). This causes problems in the function of cell because a cell cannot function normally without correct complement of chromosome. Nondisjunction can occur when chromosomes are preparing to separate prior to cell division. Types of Nondisjunction. Nondisjunction can occur during mitosis, meiosis I, or meiosis II.
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  • Oct 07,  · Usually, this phenomenon is caused by the failure of the separation of homologous chromosomes during anaphase I, or the sister chromatids during anaphase II. If the error occurred during anaphase I, the result is the presence of two gametes with a lacking chromosome and two gametes that bear two copies of the chromosome. Nondisjunction of the sex chromosomes (X or Y chromosome): Can be fatal, but many people have these karyotypes and are just fine! A. Klinefelter syndrome: 47, XXY males. Male sex organs; unusually small testes, sterile. Breast enlargement and other feminine body characteristics. Normal intelligence.
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  • Klinefelter Syndrome: It occurs due to trisomy of sex-linked chromosomes, due to the nondisjunction of paternal sex chromosomes in meiosis I. The individuals suffering from this syndrome exhibit the development of breasts as well as underdeveloped male sex characteristics. Klinefelter syndrome is the most common sex chromosome aneuploidy in humans. It represents the most frequent cause of hypogonadism and infertility in men. Most cases are caused by nondisjunction errors in paternal meiosis I. About eighty percent of individuals with this syndrome have one extra X chromosome resulting in the karyotype XXY. The remaining cases have .
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  • The results show that Charles has a trisomy of the sex chromosomes, diagnosed as XYY, which is caused by nondisjunction in the formation of the father's sperm. The nondisjunction resulted in an extra copy of the Y chromosome. The extra copy was . A man has a condition where all of his gametes undergo nondisjunction of the sex chromosomes in meiosis I, but meiosis II proceeds normally. He mates with a woman who produces all normal gametes. What is the probability that the fertilized egg will develop into a child with Turner syndrome (XO)?
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