Support Center Support Center. Bias due to misclassification in the estimation of relative risk. Am J Gastroenterol514 Mar
Dig Dis. Fatty liver has been considered the hepatic manifestation of MS 3 ; however it has been recently recognized that ectopic liver fat accumulation has independent associations with insulin resistance and the cardiovascular risk biomarkers included in the MS definition 4 — 6.
Bethesda MD : U. Race, current smoking habits, alcohol intake and educational status were obtained from a self-reported questionnaire.
Hepatic steatosis is significant for public health because it is associated with insulin resistance and type 2 diabetes development 4 — 630 Obesity Silver Spring Aug; 18 8 —5. In a reverse association study, insulin and alanine transferase levels representing liver injury were predictive of fatty liver 8.
Explore citation contexts and check if this article has been supported or disputed. ShubairDeeb J. Aside from increasing cardiovascular morbidity and mortality, progressive accumulation of fat in the liver can result in more serious liver disease, such as non-alcoholic steatohepatitis, high sex hormone binding globulin levels in women in Salem, and neoplasia 3.
Association of nonalcoholic fatty liver disease with subclinical myocardial remodeling and dysfunction: A population-based study. A larger prospective study that quantified changes in liver fat, insulin sensitivity and SHBG in men and women also showed a strong correlation between changes in liver fat and SHBG concentration An early response to reduced insulin sensitivity is production of more insulin to maintain normoglycemia; however, high insulin concentrations are initially secreted into the portal circulation where hepatocytes are the first cells exposed.
J Clin Endocrinol Metab. Weight was measured on a balance beam scale while wearing indoor clothing to the nearest 0. Open in a separate window.